4-(2-Ethoxycarbonylethyl)piperidine-1-carboxylic acid tert-butyl ester - Names and Identifiers
4-(2-Ethoxycarbonylethyl)piperidine-1-carboxylic acid tert-butyl ester - Physico-chemical Properties
Molecular Formula | C15H27NO4
|
Molar Mass | 285.38 |
Density | 1.036 |
Storage Condition | 2-8°C |
4-(2-Ethoxycarbonylethyl)piperidine-1-carboxylic acid tert-butyl ester - Introduction
4-piperidinepanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester is a compound with the chemical name 4-piperidinepanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester. The following is a description of some information about the properties, uses, preparation and safety of this compound:
Nature:
Appearance: 4-piperidinepanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester is a colorless to pale yellow liquid.
Molecular formula: C14H23NO3
Molecular weight: 253.34g/mol
Boiling point: 320-324 ℃
Melting point:-3 ℃
Use:
4-piperidinepanoic acid, 1-[(1,1-dimenthylethoxy) carbonyl]-, ethyl ester is commonly used as an intermediate in organic synthesis. It can be used as a starting material for the synthesis of pharmaceuticals, pesticides and other organic compounds.
Method:
The preparation of 4-piperidinepanoic acid, 1-[(1,1-dimenthylethoxy) carbonyl]-, ethyl ester can be carried out by the following steps:
1.4-piperidine propionate ethyl ester and sodium hydroxide are reacted in alcohol solution to generate 4-piperidine propionate sodium salt.
2.4-piperidinepropionate sodium salt reacts with dimethyl carbonate in a transesterification reaction to generate 4-Piperidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester.
Safety Information:
4-piperidinepanoic acid, 1-[(1,1-dimenthylethoxy) carbonyl]-, ethyl ester is irritating to the skin, eyes and mucous membranes, and protective measures should be taken to avoid contact. Wear appropriate personal protective equipment such as gloves, glasses and protective face masks during use or handling. If contact with skin or eyes occurs, rinse with plenty of water and seek medical help. In addition, 4-piperidinepanoic acid, 1-[(1,1-dimenthylethoxy) carbonyl]-, ethyl Lester can also cause danger through inhalation and ingestion, and should be stored in a dry, ventilated place, keep away from fire and flammable materials. In use should pay attention to follow the safety procedures.
Last Update:2024-04-09 20:52:54